Saturday 24 December 2011

PSYCHIATRIC SEQUELAE


PSYCHIATRIC SEQUELAE OF PHYSICAL DISORDERS


Physical Conditions                                     Psychiatric Sequelae

1. Vitamin Deficiency

a. Pellagra (Nicolinic Acid Deficiency)            Fatigue, Lassitude, Depression, Suicidal ideas, Paranoid ideas, Confusion, Disorientation, Delirium
b. Beriberi (Thiamine Deficiency)                             Depression, Irritability, Excitement,
                                                                                      Quarrelsomeness, Weakness, Apathy, 
                                                                                      Sleeplessness, Poor appetite, Delirium,
                                                                                      Apprehension, Confusion
c. Pernicious Anaemia (B12 deficiency)           Headache, Malaise, Fatigue, Irritability,
Depression, Paranoid Symptoms, Hallucinations

2. Metabolic Disorders  
                                                    
a. Water intoxication                                          Lassitude, Mood changes, Clouding of
    (Cellular overhydration)                                consciousness
b. Dehydration                                                    Delirium, Hallucination
c. Anoxia                                                               Anxiety, Confusion, Hallucinations
d. Hypercapnia                                                    Confusion, Disorientation,
    (COintoxication)                                            Hallucinations
e. Sodium Depletion                                            Fatigue, Apathy, Disorientation,
                                                                              Clouding of consciousness
f. Potassium Depletion                                        Depression, Suicidal ideas, Tension,
                                                                              Lethargy, Irritability
g. Porphyria                                                         Clouding of consciousness, Depression,
                                                                              Paranoid ideas, Hallucination,
h. Hepatic Failure                                                Euphoria or Depression, Delirium,
                                                                              Emotional lability and Incontinence
i. Uraemia                                                            Delirium, Restlessness, Psychosis
j. Cardiac failure                                                 Impaired Concentration and Memory,
                                                                              Emotional lability, Delirium

3. Endocrine Disturbances

a. Hypothyroidism                                              Loss of interest, Apathy, Dullness,
                                                                              Slowness of Comprehension, Lethargy,
                                                                              Psychomotor Retardation, Depressive
                                                                              and Paranoid ideas,  Memory deficits.
b. Hyperthyroidism                                             Anxiety, Tension, Restlessness
c. Hypoparathyroidism                                       Anxiety, Mood disturbances, Psychosis
                                                                              with Delusions and Hallucinations
d. Hyperparathyroidism                                    Impaired concentration, Emotional
                                                                              lability, Irritability, Depression,
                                                                              Paranoid ideas
e. Hypopituitarism                                              Indifference, Apathy, Lethargy,
                                                                              Depression, Irritability, Memory
                                                                              disturbances
      f. Hypoglycemia                                                   Anxiety, Confusion, Psychomotor
                                                                                    agitation, Delusions, Hallucinations
      g. Diabetes Mellitus                                             Lethargy, Irritability, Depression
      h. Cushing’s Syndrome                                       Acute anxiety, Depression, Agitation,
                                                                                    Paranoid delusions, Excitement,
                                                                                    Emotional lability
       i. Addison’s Disease                                           Apathy, Diminution of drives,
                                                                                    Paranoid ideas, Delirium, Depression,
                                                                              Memory Disturbances

4. Infection

a. HIV Infection                                                  Anxiety, Depression
b. Viral infection                                                Depression
c. Rheumatic fever                                            Apathy, Sulkiness, Irritability, Emotional lability
d. Pulmonary Tuberculosis                             Malaise, Fatigue, Euphoria
e. Malaria                                                          Excitement, Delirium
f. Enteric Fever                                             Clouding of consciousness, Hypo-manic symptoms   or Depression
g. Meningitis                                                   Irritability, Emotional disturbances, Delirium,
and encephalitis                             Delusional Ideas, Hallucination, Confusion
                                   
      h. Septicaemia                                              Apathy or Euphoria, Drowsiness

5.      Collagen Diseases    
                                                                                                                 
SLE                                                         Emotional lability, Organic brain syndrome, Depression


6.      Neurological Illnesses

a. Disseminated Sclerosis                          Euphoria, Depression. Memory disturbances,
                                                                     Irritability

b. Parkinsonism                                         Depression

c. Brain Tumors                                         Mood changes, Psychosis, Memory disturbances,
                                                                     Clouding of consciousness

d. Cerebrovascular Accidents             Irritability, Apathy, Lability of mood, Depression Aggressiveness

e. Brain Injury                                      Memory disturbances, Disorientation, Clouding of       consciousness, Delirium, Dementia

f. Subdural Haematoma                           Poor concentration, Fluctuating consciousness,
                                                                          Excitement, Somnolence, Memory defects,
                                                                          Apathy, Delirium

7. Other Illnesses

a. Essential Hypertension                    Fatigue, Anxiety, Irritability, Depression,
                                                               Impaired Concentration

b. Myocardial Infarction                      Anxiety, Depression, Mood     changes

c. Bronchial Asthma                             Irritability, Depression

d. Malignancy                                        Depression, Cognitive disturbances

8. Drugs
  1. Reserpine                                         Depression
  2. Methyldopa                                      Depression, Nightmares
  3. Clonidine                                          Depression
  4. Phenothiazines                               Depression
  5. Analgesics                                        Depression
  6. Levodopa                                         Depression, Hallucinations, Confusion
  7. Oral Contraceptives                      Depression, At times Elation
h.    Corticosteriods                            Elation, Euphoria or Depression, Mania, Psychosis with Hallucination and Delusions
i. INH                                                      Elation, Mania
j. Amphetamines                                   Hallucinations, Paranoid Ideas, Agitation,
                                                               Anxiety, Manic Symptoms, Depression
k. Anabolic Steroids                             Psychosis, Mania, Depression, Paranoia
l. Anticholinergics                                 Confusion, Memory Loss, Disorientation,
   and Atropine                                     Auditory and Visual Hallucinations
Fear, Incoherent Speech, Delirium with high fever, Flushed dry skin
m. Anti Convulsants                             Agitation, Confusion, Delirium, Depression,
                                                               Psychosis
n. Antihistamine H20 - Blockers          Hallucinations
o. Barbiturates                                     Excitement, Hyperactivity, Visual Hallucinations
                                                               Depression, Delirium, Tremens like Syndrome
p. Benzodiazepines                              Rage, Hostility, Paranoia, Hallucinations,
                                                               Delirium
q. Beta-Adrenergic Blockers               Psychosis, Delirium, Hallucinations
r. Caffeine                                              Anxiety, Confusion, Psychotic Symptoms
s. Chloroquine                                      Confusion, Delusion, Hallucinations, Mania
t. Dapsone                                             Insomnia, Agitation, Hallucinations, Mania,
                                                               Depression
u. Digitalis Glycosides                          Delirium, Depression, Decreased Libido, Psychosis
v. Disulfiram                                         Delirium, Depression, Psychosis
w. Estrogens                                         Panic Attacks, Depression
x. Isoniazid                                            Psychosis, Hallucinations
y. Metronidazole                                  Depression, Agitation, Uncontrollable, Crying
z. Narcotics                                           Nightmares, Agitation, Dysphoria, Paranoia
z1. Nosteroidal                                     Depression, Paranoia, Psychosis
     Anti-inflammatory Drugs  
      z2. Quindine                                          Confusion, Agitation, Psychosis
      z3. Sulfonamides                                  Confusion, Depression, Euphoria, Hallucinations


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